Atorvastatin (ATR) is a poorly water-soluble anti-hyperlipidemic drug.The drug belongs to the class II group according to the biopharmaceutical classification system (BCS) with opi the color that keeps on giving low bioavailability due to its low solubility.Solid dispersion is an effective technique for enhancing the solubility and dissolution of d

ABSTRACT: Histomonas meleagridis and Tetratrichomonas gallinarum are two protozoans responsible for mortality associated with typhlohepatitis in poultry.In this study, the etiology of high mortality in Chukar partridges suspected of infection with these agents was investigated pathologically and molecularly.Twelve healthy partridges during the layi

This article deals with the way customers perceive individual non-direct response printed leaflets and it is simultaneously focused on the question whether this material has any importance in general for customers during their purchase realization.The research is further concerned with the issue of the differences between customers living in family

AimWe recently described a human blood microbiome and a connection between pentair hose this microbiome and the onset of diabetes.The aim of the current study was to assess the association between blood microbiota and incident cardiovascular disease.Methods and resultsD.E.S.I.R.is a longitudinal study with the primary aim of describing the natural

The combination cancer therapy is a new strategy to circumvent drug resistance for the treatment of high metastasis and advanced malignancies.Herein, we developed a synthesized compound MPT0B451 that display inhibitory effect against histone deacetylase (HDAC) 6 and tubulin assembly.Our data demonstrated that MPT0B451 significantly inhibited cancer